4
Bioelectromagnetism
TABLE 1.1 Important Events in the History of Bioelectromagnetism
1493
Paracelsus – medical treatment with magnet as vital stones
1600
Gilbert – De Magnete
1786
Galvani – animal electricity from frog experiment
1793
Volta – Volta’s pile
1830
Faraday – Induction law
1849
Du Bois-Reymond – medical application of induction coil
1864
Maxwell – the electromagnetic feld theory
1891
Tesla and d’Arsoval – medical application of high-frequency current
1896
D’Arsonval – magnetophosphenes
l925
Schliephake – medical application of shortwave
1953
Yasuda – piezoelectricity of bone
1959
Collin – magnetic stimulation of nerves
1960
Human health efect of ELF electric feld
1962
Bassett – electric stimulation of bone fracture
1979
Human health efects of ELF magnetic feld
1985
Barker – magnetic motor co1tex stimulation
1988
Ueno – magnetic stimulation of the fgure-eight coil
2000
Human health efect of high-frequency feld
2003
MRI medical application
theory by Maxwell and its formulation by Oliver Heaviside, the existence of the electromagnetic wave
was discovered experimentally by Heinrich Rudolf Hertz in 1888. Maxwell equations are a set of four
equations which describe an electromagnetic wave: Gauss’s law, Gauss’s law for magnetism, Faraday’s
law and Ampère’s law. In 1897, using electromagnetic waves, Guglielmo Marconi was able to send radio
transmission signals to a tugboat at a distance over 18 miles (29 km) from the Bristol Channel, England.
In 1899, Marconi sent the frst international wireless message from Dover, England, to Wimereux,
France. Within 4 years, he sent a wireless message across the Atlantic Ocean. Tese historical events
opened a new era for the use of electromagnetic waves.
Table 1.1 shows the discovery timeline and other important events in the history of bioelectromag
netism. Tey are divided into theory, instrumentation, stimulation and measurement in the feld of the
interactions between electromagnetic phenomena and the living body. Fundamental research studies
on the medical application of magnetic phenomena were promoted, as seen by the magnetic stimula
tion of the nerve and the development of techniques used in clinical applications. As shown in Table 1.1,
the history of bioelectromagnetism is nearly identical to that of electromagnetism. Tis means that the
instrumentation based on bioelectromagnetic phenomena was quickly developed. Tese instruments
were able to measure both electric and magnetic signals in biological systems.
Afer the frst electromagnetic experiments on biological systems were conducted during the course
of the nineteenth century, electromagnetism and bioelectromagnetism share the same long research
history. Since then, what is the interaction between electromagnetism and living organisms, how elec
tromagnetism afects living organisms and how living organisms use electromagnetic information been
of interest to many scientists. Tese interests have led to numerous experiments and theoretical stud
ies, and the concept of bioelectromagnetism was established through such research developments. Te
details of the history of bioelectromagnetism will be given in Chapter 2.
Although bioelectromagnetism has a long research history with help from electromagnetism, the
term “bioelectromagnetism” gained popularity in scientifc communities around 1980. Te time around
1980 was when the Bioelectromagnetics Society (BEMS) was founded. Te BEMS covers research related
to electromagnetic phenomena ranging from static felds through the radio frequency feld up to tera
hertz frequencies and acoustic energy with biological systems.